Across TCGA patient cohorts, PCYT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,338 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCYT2-associated proteins across cancer lineages are RPTOR, TACO1, and MCCC1. Each is linked with PCYT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCYT2-to-partner and partner-to-PCYT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT2→partner) and Y-score (partner→PCYT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPTOR →	+0.208	+0.478	<.001	.001	3	6
CCRCC	TACO1 →	+0.446	+0.662	<.001	<.001	3	5
OV	MCCC1 →	+0.425	+0.362	<.001	.005	3	4
GBM	MIPEP →	+0.320	+0.326	<.001	.001	3	4
OV	MRPL11 →	+0.505	+0.684	<.001	<.001	3	4
LSCC	MRPL15 →	+0.354	+0.609	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,338 associations by consensus.

Exploration

PCYT2 survival (RNA) · tumor vs normal (RNA) · all PCYT2 data types