Across TCGA cell cohorts, PCYT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,207 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PCYT2-associated GO terms across cancer lineages are Cholesterol biosynthetic process, Zymosterol metabolic process, and Zymosterol biosynthetic process. Each is linked with PCYT2 in more than 15 cancer types. Because this analysis shows association rather than direction, both PCYT2-to-partner and partner-to-PCYT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT2→partner) and Y-score (partner→PCYT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cholesterol biosynthetic process →	+0.185	+0.907	<.001	<.001	3	16
BONE	Zymosterol metabolic process →	+0.222	+0.963	.001	.001	3	16
BONE	Zymosterol biosynthetic process →	+0.222	+0.963	.001	.001	3	16
LUNG_NSCLC_LUAD	Secondary alcohol biosynthetic process →	+0.185	+0.907	<.001	<.001	3	16
BONE	Isopentenyl diphosphate biosynthetic process →	+0.217	+1.105	.002	<.001	3	15
BONE	Isopentenyl diphosphate metabolic process →	+0.217	+1.105	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,207 associations by consensus.

Exploration

PCYT2 survival (RNA) · tumor vs normal (RNA) · all PCYT2 data types