PCYT1B

Across TCGA patient cohorts, PCYT1B RNA expression is significantly associated with the RNA expression of many other genes, with 16,824 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PCYT1B-associated genes across cancer lineages are IKZF4, MAP1A, and SALL2. Each is linked with PCYT1B in more than 26 cancer types. Because this analysis shows association rather than direction, both PCYT1B-to-partner and partner-to-PCYT1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCYT1B versus IKZF4 in ACC, with a Pearson correlation of 0.49.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT1B→partner) and Y-score (partner→PCYT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	IKZF4 →	+1.184	+1.694	<.001	<.001	3	27
MESO	MAP1A →	+1.596	+1.128	<.001	<.001	3	26
SARC	SALL2 →	+1.949	+1.906	<.001	<.001	3	26
SARC	RAB9B →	+2.125	+1.562	<.001	<.001	3	26
UCS	TSPY26P →	+1.843	+1.580	<.001	<.001	3	26
ESCA	SMO →	+2.239	+1.499	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,824 associations by consensus.

PCYT1B vs IKZF4 — ACC

Explore this scatter interactively →