PCYT1B

Across TCGA patient cohorts, PCYT1B RNA expression is significantly associated with the protein abundance of many other proteins, with 19,956 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCYT1B-associated proteins across cancer lineages are MAP1A, PFN2, and MAP1A_S1600. Each is linked with PCYT1B in more than 5 cancer types. Because this analysis shows association rather than direction, both PCYT1B-to-partner and partner-to-PCYT1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCYT1B versus MAP1A in UCEC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT1B→partner) and Y-score (partner→PCYT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP1A →	+0.694	+1.181	<.001	<.001	3	6
LSCC	PFN2 →	+0.695	+1.067	<.001	<.001	3	5
LSCC	MAP1A_S1600 →	+1.550	+1.144	<.001	<.001	3	5
HNSC	UCHL1 →	+1.246	+0.658	<.001	.004	3	5
GBM	SAMSN1 →	-0.509	-0.668	<.001	<.001	3	5
BRCA	SDC4 →	-0.619	-0.457	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,956 associations by consensus.

PCYT1B vs MAP1A — UCEC

Explore this scatter interactively →