PCYOX1

Across TCGA cell cohorts, PCYOX1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCYOX1-associated genes across cancer lineages are MYL7, BTBD16, and C16orf92. Each is linked with PCYOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCYOX1-to-partner and partner-to-PCYOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL7 grouped by PCYOX1-low versus PCYOX1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYOX1→partner) and Y-score (partner→PCYOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYL7 →	+0.063	+4.339	<.001	.002	3	1
BLOOD_Leukemia	BTBD16 →	+0.094	+3.959	<.001	.005	3	1
BLOOD_Leukemia	C16orf92 →	+0.145	+4.037	<.001	.004	3	1
BLOOD_Leukemia	INSM2 →	+0.239	+3.769	<.001	.008	3	1
BLOOD_Leukemia	FAM71B →	+0.019	+4.060	<.001	.003	3	1
BLOOD_Leukemia	KLK15 →	+0.606	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MYL7 by PCYOX1 expression — BLOOD_Leukemia

Explore this box plot interactively →