PCP4L1

Across TCGA pan-cancer cohorts, PCP4L1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PCP4L1 data layer compared with 19 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PCP4L1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PCP4L1 expression acts as an unfavorable survival marker.

COAD, DLBC, and SKCM are the cancer types where PCP4L1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.045	0.871	<.001	48	view →
DLBC	DFS	Median	III,IV	0.137	0.790	<.001	15	view →
SKCM	OS	Median	All	0.210	0.781	<.001	14	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PCP4L1–COAD (OS)

Open the COAD breakdown →