Across TCGA pan-cancer cohorts, PCP4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PCP4 data layer compared with 19 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PCP4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PCP4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

COAD, LUAD, and HNSC are the cancer types where PCP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.908	1.000	.019	24	view →
LUAD	DFS	Quartile	All	0.576	0.963	.026	3	view →
HNSC	OS	Quartile	IV	0.853	0.355	.019	2	view →
LSCC	DFS	Median	II,III,IV	0.999	0.860	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PCP4 tumor-vs-normal RNA expression · all PCP4 data types