Across TCGA patient cohorts, PCP4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,212 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCP4-associated genes across cancer lineages are MAPK4, LYVE1, and GPM6A. Each is linked with PCP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCP4-to-partner and partner-to-PCP4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCP4→partner) and Y-score (partner→PCP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAPK4 →	+0.956	+0.838	.006	.001	3	4
COAD	LYVE1 →	+1.110	+1.000	.006	.002	3	4
COAD	GPM6A →	+0.919	+1.121	.004	.001	3	4
GBM	RCAN2 →	+1.493	+0.902	<.001	<.001	3	4
GBM	TCEAL6 →	+1.601	+1.008	<.001	<.001	3	4
BRCA	BEX2 →	+1.807	+1.610	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,212 associations by consensus.

Exploration

PCP4 survival (RNA) · tumor vs normal (RNA) · all PCP4 data types