PCP2

Across TCGA patient cohorts, PCP2 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCP2-associated genes across cancer lineages are SOD1P2, MIR8052, and LINC01248. Each is linked with PCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCP2-to-partner and partner-to-PCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOD1P2 grouped by PCP2-low versus PCP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCP2→partner) and Y-score (partner→PCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SOD1P2 →	+0.228	+5.145	.005	.007	3	2
BRCA	MIR8052 →	+0.501	+7.731	<.001	.009	3	1
COAD	LINC01248 →	+0.227	+5.516	.001	.004	3	1
COAD	MTATP6P20 →	+0.195	+5.212	<.001	.007	3	1
COAD	TMEM97P2 →	+0.237	+5.516	<.001	.004	3	1
COAD	RNU1-30P →	+0.436	+5.435	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

SOD1P2 by PCP2 expression — COAD

Explore this box plot interactively →