PCP2

Across TCGA patient cohorts, PCP2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCP2-associated genes across cancer lineages are Preadipocytes, Basophils, and Endothelial cells. Each is linked with PCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCP2-to-partner and partner-to-PCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by PCP2-low versus PCP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCP2→partner) and Y-score (partner→PCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Preadipocytes →	+0.049	+4.169	.008	.027	3	1
UCEC	Basophils →	+0.242	+3.169	.009	.020	3	1
UCEC	Endothelial cells →	-0.044	-3.127	.035	.020	1	1
UCEC	mv Endothelial cells →	-0.032	-3.159	.013	.020	1	1
UCEC	Skeletal muscle →	+0.052	+3.180	.029	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Preadipocytes by PCP2 expression — COAD

Explore this box plot interactively →