PCP2

Across TCGA cell cohorts, PCP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,479 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PCP2-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Regulation of myoblast fusion, and Establishment of epithelial cell apical/basal polarity. Each is linked with PCP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PCP2-to-partner and partner-to-PCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by PCP2-low versus PCP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCP2→partner) and Y-score (partner→PCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytotoxic T cell degranulation →	+0.314	+0.616	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.124	+0.655	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Establishment of epithelial cell apical/basal polarity →	-0.219	-0.588	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.120	+0.674	<.001	<.001	3	8
BONE	Cellular response to lead ion →	+0.177	+0.399	<.001	.004	3	7
BONE	Negative regulation of transcription elongation by RNA polymerase II →	+0.105	+0.563	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,479 associations by consensus.

Cytotoxic T cell degranulation by PCP2 expression — BONE

Explore this box plot interactively →