PCOLCE2

Across TCGA patient cohorts, PCOLCE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,706 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PCOLCE2-associated proteins across cancer lineages are HSPG2, NID2, and PLOD1. Each is linked with PCOLCE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCOLCE2-to-partner and partner-to-PCOLCE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCOLCE2 versus HSPG2 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCOLCE2→partner) and Y-score (partner→PCOLCE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSPG2 →	+0.444	+1.283	.002	.002	3	6
GBM	NID2 →	+0.536	+1.119	<.001	<.001	3	6
GBM	PLOD1 →	+0.571	+1.429	.003	<.001	3	5
OV	PLOD2 →	+1.188	+1.125	<.001	<.001	3	5
BRCA	RSU1 →	+0.393	+1.202	<.001	<.001	3	5
COAD	C8G →	+0.517	+0.921	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,706 associations by consensus.

PCOLCE2 vs HSPG2 — BRCA

Explore this scatter interactively →