PCOLCE2

Across TCGA patient cohorts, PCOLCE2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,489 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCOLCE2-associated genes across cancer lineages are DRP2, CLIP3, and MAP1B. Each is linked with PCOLCE2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCOLCE2-to-partner and partner-to-PCOLCE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCOLCE2 versus DRP2 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCOLCE2→partner) and Y-score (partner→PCOLCE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DRP2 →	+0.681	+0.924	.002	.005	3	3
HNSC	CLIP3 →	+1.061	+0.755	.001	<.001	3	3
LSCC	MAP1B →	+1.268	+0.770	.003	.002	3	3
LUAD	ALDH1L2 →	+0.958	+0.542	<.001	.006	3	3
LUAD	LARP6 →	+0.806	+0.808	<.001	<.001	3	3
GBM	SLAMF9 →	+1.061	+1.093	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,489 associations by consensus.

PCOLCE2 vs DRP2 — OV

Explore this scatter interactively →