PCNX4

Across TCGA patient cohorts, PCNX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,294 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCNX4-associated proteins across cancer lineages are MTHFD1, AKT1, and SEC23B. Each is linked with PCNX4 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCNX4-to-partner and partner-to-PCNX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNX4 versus MTHFD1 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX4→partner) and Y-score (partner→PCNX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTHFD1 →	+0.355	+0.413	<.001	<.001	3	7
COAD	AKT1 →	+0.296	+0.458	<.001	<.001	3	7
OV	SEC23B →	-0.382	-0.632	<.001	<.001	3	7
OV	PPIF →	-0.596	-0.589	<.001	<.001	3	6
GBM	PPP2R5E →	+0.366	+0.466	<.001	<.001	3	6
GBM	PPP4R3A →	+0.277	+0.328	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,294 associations by consensus.

PCNX4 vs MTHFD1 — GBM

Explore this scatter interactively →