PCNX4

Across TCGA patient cohorts, PCNX4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,284 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCNX4-associated genes across cancer lineages are ACKR2, SYTL3, and SELENOP. Each is linked with PCNX4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCNX4-to-partner and partner-to-PCNX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNX4 versus ACKR2 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX4→partner) and Y-score (partner→PCNX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACKR2 →	-1.929	-0.700	<.001	<.001	3	3
GBM	SYTL3 →	-0.465	-0.359	.001	.001	3	3
LUAD	SELENOP →	-1.168	-0.506	.006	.001	3	3
GBM	PIK3IP1 →	-0.465	-0.300	.002	.009	3	2
OV	GATA3 →	-0.686	-0.498	.002	.003	3	2
GBM	VSIR →	-0.565	-0.381	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

PCNX4 vs ACKR2 — UCEC

Explore this scatter interactively →