PCNX4

Across TCGA patient cohorts, PCNX4 mutation is significantly associated with the RNA expression of many other genes, with 4,388 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCNX4-associated genes across cancer lineages are CDKN3, RBFA, and MRPS15. Each is linked with PCNX4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCNX4-to-partner and partner-to-PCNX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDKN3 grouped by PCNX4-low versus PCNX4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX4→partner) and Y-score (partner→PCNX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+0.666	+2.584	<.001	<.001	3	3
UCEC	RBFA →	+0.309	+1.856	.003	.004	3	3
UCEC	MRPS15 →	+0.300	+2.705	.004	<.001	3	3
UCEC	TXNL4A →	+0.370	+2.675	<.001	<.001	3	3
UCEC	KIF2C →	+0.637	+1.818	.001	<.001	3	3
SKCM	LINC02460 →	+0.069	+2.683	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,388 associations by consensus.

CDKN3 by PCNX4 expression — UCEC

Explore this box plot interactively →