Across TCGA patient cohorts, PCNX3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,153 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PCNX3-associated genes across cancer lineages are GUCY1A1, DENND6B, and GPR82. Each is linked with PCNX3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCNX3-to-partner and partner-to-PCNX3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX3→partner) and Y-score (partner→PCNX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GUCY1A1 →	-0.713	-0.342	.004	.006	3	3
LUAD	DENND6B →	-0.515	-0.319	.007	.005	3	2
LSCC	GPR82 →	-0.667	-0.280	.001	.001	3	2
PDAC	CAPN7 →	-0.387	-0.520	.003	.003	3	2
PDAC	PREPL →	-0.435	-0.592	.002	<.001	3	2
UCEC	UCN →	-0.878	-0.669	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,153 associations by consensus.

Exploration

PCNX3 survival (RNA) · tumor vs normal (RNA) · all PCNX3 data types