Across TCGA patient cohorts, PCNX3 mutation is significantly associated with the RNA expression of many other genes, with 3,670 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCNX3-associated genes across cancer lineages are ZCCHC9, MRPL39, and NCAPH2. Each is linked with PCNX3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCNX3-to-partner and partner-to-PCNX3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX3→partner) and Y-score (partner→PCNX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZCCHC9 →	+0.473	+2.516	.009	.009	3	4
UCEC	MRPL39 →	+0.339	+2.687	.002	<.001	3	4
UCEC	NCAPH2 →	+0.501	+1.893	<.001	<.001	3	4
COAD	SNRPD3 →	+0.283	+3.615	.007	.001	3	4
UCEC	EXOSC9 →	+0.400	+2.687	.001	<.001	3	4
COAD	YARS1 →	+0.340	+2.348	.007	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

Exploration

PCNX3 survival (RNA) · tumor vs normal (RNA) · all PCNX3 data types