Across TCGA patient cohorts, PCNX3 mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PCNX3-associated genes across cancer lineages are GAPDH, Caspase-7-cleavedD198, and eEF2. Each is linked with PCNX3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCNX3-to-partner and partner-to-PCNX3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX3→partner) and Y-score (partner→PCNX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GAPDH →	+1.137	+2.816	.001	.036	3	4
STAD	Caspase-7-cleavedD198 →	+1.342	+3.459	<.001	.004	3	4
STAD	eEF2 →	+0.551	+3.321	<.001	.009	3	3
STAD	EGFR_pY1068 →	-0.375	-3.321	.030	.009	3	3
STAD	NF2 →	+0.296	+3.459	<.001	.005	3	3
STAD	NF-kB-p65_pS536 →	-0.595	-3.169	.003	.018	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration

PCNX3 survival (RNA) · tumor vs normal (RNA) · all PCNX3 data types