PCNX2

Across TCGA patient cohorts, PCNX2 protein abundance is significantly associated with the RNA expression of many other genes, with 609 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCNX2-associated genes across cancer lineages are SH3BP1, CRYBB1, and AP1B1. Each is linked with PCNX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCNX2-to-partner and partner-to-PCNX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNX2 versus SH3BP1 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX2→partner) and Y-score (partner→PCNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SH3BP1 →	+0.705	+0.652	.003	.004	3	1
GBM	CRYBB1 →	+1.027	+0.644	.001	.001	3	1
GBM	AP1B1 →	+0.604	+0.632	<.001	.001	3	1
GBM	KIAA0930 →	+1.425	+0.847	<.001	<.001	3	1
GBM	DESI1 →	+0.498	+0.625	.006	.006	3	1
GBM	CHGA →	+1.925	+0.603	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 609 associations by consensus.

PCNX2 vs SH3BP1 — GBM

Explore this scatter interactively →