PCNX1

Across TCGA cell cohorts, PCNX1 mutation is significantly associated with the RNA expression of many other genes, with 1,201 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCNX1-associated genes across cancer lineages are C17orf75, PBK, and ZNF286B. Each is linked with PCNX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCNX1-to-partner and partner-to-PCNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C17orf75 grouped by PCNX1-low versus PCNX1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNX1→partner) and Y-score (partner→PCNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C17orf75 →	+0.603	+2.489	.007	.007	3	3
BLOOD_Leukemia	PBK →	+1.209	+2.489	.008	.007	3	3
OVARY	ZNF286B →	+0.912	+3.321	.001	.005	3	3
LARGE_INTESTINE	ENHO →	+0.583	+2.000	.001	.009	3	3
LARGE_INTESTINE	NIPSNAP1 →	+0.784	+2.807	<.001	<.001	3	3
LARGE_INTESTINE	ATP2A1 →	+0.700	+2.459	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,201 associations by consensus.

C17orf75 by PCNX1 expression — BLOOD_Leukemia

Explore this box plot interactively →