PCNT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCNT RNA expression is significantly associated with the protein abundance of many other proteins, with 12,091 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCNT-associated proteins across cancer lineages are WIZ, MED8, and TRRAP. Each is linked with PCNT in more than 4 cancer types. Because this analysis shows association rather than direction, both PCNT-to-partner and partner-to-PCNT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNT versus WIZ in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNT→partner) and Y-score (partner→PCNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWIZ →+0.418+0.554<.001<.00135
BRCAMED8 →+0.257+0.466<.001.00135
GBMTRRAP →+0.250+0.448<.001<.00135
GBMBUB3 →+0.237+0.331.002.00335
GBMRBM39 →+0.186+0.343<.001<.00135
GBMPNN →+0.340+0.467.002<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,091 associations by consensus.

PCNT vs WIZ — GBM

Per-sample scatter of PCNT vs WIZ in GBM (Pearson r = 0.42).

Explore this scatter interactively →

Exploration