PCNT

Across TCGA patient cohorts, PCNT protein abundance is significantly associated with the RNA expression of many other genes, with 8,883 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCNT-associated genes across cancer lineages are MCM3AP, CXCL8, and SLC2A1. Each is linked with PCNT in more than 4 cancer types. Because this analysis shows association rather than direction, both PCNT-to-partner and partner-to-PCNT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCNT versus MCM3AP in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNT→partner) and Y-score (partner→PCNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MCM3AP →	+0.857	+0.263	.004	<.001	3	5
GBM	CXCL8 →	-1.803	-0.198	.004	<.001	3	5
LSCC	SLC2A1 →	-1.387	-0.225	<.001	<.001	3	4
HNSC	AOX1 →	+1.180	+0.197	<.001	<.001	3	4
HNSC	N4BP2L1 →	+0.606	+0.147	.001	.003	3	4
HNSC	CBLC →	-0.821	-0.166	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,883 associations by consensus.

PCNT vs MCM3AP — OV

Explore this scatter interactively →