PCNT

Across TCGA cell cohorts, PCNT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,529 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCNT-associated GO terms across cancer lineages are Chromosome condensation, Microtubule organizing center organization, and Microtubule polymerization or depolymerization. Each is linked with PCNT in more than 18 cancer types. Because this analysis shows association rather than direction, both PCNT-to-partner and partner-to-PCNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome condensation grouped by PCNT-low versus PCNT-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNT→partner) and Y-score (partner→PCNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chromosome condensation →	+0.169	+0.962	.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.088	+0.961	<.001	.001	3	17
BONE	Microtubule polymerization or depolymerization →	+0.127	+1.306	<.001	<.001	3	17
BONE	Regulation of centrosome cycle →	+0.084	+1.152	<.001	<.001	3	17
STOMACH	Microtubule polymerization →	+0.120	+1.080	<.001	.001	3	17
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.109	+1.306	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,529 associations by consensus.

Chromosome condensation by PCNT expression — BONE

Explore this box plot interactively →