PCNP

Across TCGA pan-cancer cohorts, PCNP Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PCNP data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PCNP Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated PCNP expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LUAD, and BLCA are the cancer types where PCNP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.627	.012	32	view →
LUAD	OS	Median	All	0.245	0.835	<.001	18	view →
BLCA	DFS	Median	III,IV	0.146	0.574	.001	12	view →
PCPG	DFS	Median	All	0.070	0.936	<.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PCNP–UCEC (DFS)

Open the UCEC breakdown →