Across TCGA cell cohorts, PCMTD2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCMTD2-associated genes across cancer lineages are OR3A2, MAGEB4, and MYOD1. Each is linked with PCMTD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCMTD2-to-partner and partner-to-PCMTD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCMTD2→partner) and Y-score (partner→PCMTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR3A2 →	+0.030	+4.906	<.001	.006	3	1
LARGE_INTESTINE	MAGEB4 →	+0.022	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MYOD1 →	+0.015	+4.684	<.001	.002	3	1
LARGE_INTESTINE	STRA8 →	+0.161	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	DAZ2 →	+0.252	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

PCMTD2 survival (RNA) · tumor vs normal (RNA) · all PCMTD2 data types