Across TCGA pan-cancer cohorts, PCMTD1P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PCMTD1P2’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where PCMTD1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types PCMTD1P2 is over-expressed in tumor, although a few such as PRAD and THCA show the opposite, repressed pattern.
PRAD and THCA are the cancer types where PCMTD1P2 tumor–normal differential expression is most reproducible.