PCMTD1

Across TCGA patient cohorts, PCMTD1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,047 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCMTD1-associated genes across cancer lineages are CDC20, NDC80, and MYBL2. Each is linked with PCMTD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCMTD1-to-partner and partner-to-PCMTD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCMTD1 versus CDC20 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCMTD1→partner) and Y-score (partner→PCMTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC20 →	-1.529	-0.463	<.001	<.001	3	7
BRCA	NDC80 →	-1.077	-0.419	<.001	.002	3	7
LUAD	MYBL2 →	-1.631	-0.418	<.001	<.001	3	6
UCEC	KIF18A →	-0.773	-0.432	<.001	<.001	3	6
OV	CDCA8 →	-1.080	-0.436	<.001	.001	3	6
BRCA	BORA →	-0.661	-0.461	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,047 associations by consensus.

PCMTD1 vs CDC20 — BRCA

Explore this scatter interactively →