PCMTD1

Across TCGA cell cohorts, PCMTD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,072 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCMTD1-associated GO terms across cancer lineages are Negative regulation of protein localization to centrosome, Negative regulation of macroautophagy, and Cilium movement involved in cell motility. Each is linked with PCMTD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PCMTD1-to-partner and partner-to-PCMTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to centrosome grouped by PCMTD1-low versus PCMTD1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCMTD1→partner) and Y-score (partner→PCMTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of protein localization to centrosome →	+0.148	+0.885	.001	.003	3	17
OESOPHAGUS	Negative regulation of macroautophagy →	+0.100	+1.568	.004	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.147	-1.393	<.001	<.001	3	16
STOMACH	Process utilizing autophagic mechanism →	+0.086	+1.266	.001	<.001	3	15
STOMACH	Autophagy →	+0.086	+1.266	.001	<.001	3	15
OESOPHAGUS	Golgi organization →	+0.088	+1.707	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

Negative regulation of protein localization to centrosome by PCMTD1 expression — LUNG_SCLC

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