PCMT1

Across TCGA patient cohorts, PCMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,915 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCMT1-associated genes across cancer lineages are SHPRH, KPNA5, and GINM1. Each is linked with PCMT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCMT1-to-partner and partner-to-PCMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCMT1 versus SHPRH in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCMT1→partner) and Y-score (partner→PCMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SHPRH →	+0.490	+0.363	<.001	<.001	3	5
GBM	KPNA5 →	+0.645	+0.380	<.001	<.001	3	5
BRCA	GINM1 →	+0.548	+0.344	<.001	.001	3	5
GBM	TUBE1 →	+0.396	+0.288	<.001	<.001	3	5
LSCC	DOP1A →	+0.471	+0.174	.001	<.001	3	5
GBM	FBXL4 →	+0.541	+0.391	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,915 associations by consensus.

PCMT1 vs SHPRH — GBM

Explore this scatter interactively →