PCLAF

Across TCGA patient cohorts, PCLAF protein abundance is significantly associated with the RNA expression of many other genes, with 5,302 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCLAF-associated genes across cancer lineages are FAM83D, CENPI, and NCAPD2. Each is linked with PCLAF in more than 3 cancer types. Because this analysis shows association rather than direction, both PCLAF-to-partner and partner-to-PCLAF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCLAF versus FAM83D in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCLAF→partner) and Y-score (partner→PCLAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM83D →	+1.544	+0.840	<.001	<.001	3	4
GBM	CENPI →	+0.951	+0.674	<.001	<.001	3	4
UCEC	NCAPD2 →	+0.807	+0.749	.002	.003	3	4
GBM	ASF1B →	+1.506	+1.076	<.001	<.001	3	4
BRCA	NCAPG →	+1.248	+0.603	<.001	<.001	3	4
BRCA	FOXM1 →	+1.504	+0.823	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,302 associations by consensus.

PCLAF vs FAM83D — UCEC

Explore this scatter interactively →