PCK1

Across TCGA patient cohorts, PCK1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,100 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCK1-associated genes across cancer lineages are RAB5CP1, SLC19A3, and FCGRT. Each is linked with PCK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCK1-to-partner and partner-to-PCK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCK1 versus RAB5CP1 in LUAD, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCK1→partner) and Y-score (partner→PCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RAB5CP1 →	-1.316	-1.782	.002	<.001	3	3
COAD	SLC19A3 →	+1.456	+0.421	<.001	<.001	3	3
BRCA	FCGRT →	+0.909	+0.825	.004	.003	3	2
COAD	BTNL8 →	+0.994	+0.376	.004	.005	3	2
CCRCC	IRF6 →	+0.994	+0.530	.001	<.001	3	2
BRCA	ABCG2 →	+0.659	+0.993	.009	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,100 associations by consensus.

PCK1 vs RAB5CP1 — LUAD

Explore this scatter interactively →