PCK1

Across TCGA cell cohorts, PCK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,534 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCK1-associated GO terms across cancer lineages are Intestinal lipid absorption, NADP+ biosynthetic process, and Protein transport within lipid bilayer. Each is linked with PCK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCK1-to-partner and partner-to-PCK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal lipid absorption grouped by PCK1-low versus PCK1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCK1→partner) and Y-score (partner→PCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intestinal lipid absorption →	-0.222	-0.143	<.001	.006	3	5
LARGE_INTESTINE	NADP+ biosynthetic process →	+0.182	+1.473	<.001	.004	3	5
LARGE_INTESTINE	Protein transport within lipid bilayer →	+0.329	+1.628	<.001	<.001	3	5
CNS	Base-excision repair, gap-filling →	+0.067	+0.126	.001	.009	3	4
LUNG_NSCLC_LUAD	Kidney mesenchymal cell proliferation →	-0.219	-0.204	<.001	.008	3	4
LUNG_NSCLC_LUAD	Metanephric mesenchymal cell proliferation involved in metanephros development →	-0.219	-0.204	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,534 associations by consensus.

Intestinal lipid absorption by PCK1 expression — BONE

Explore this box plot interactively →