PCIF1

Across TCGA pan-cancer cohorts, PCIF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PCIF1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PCIF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PCIF1 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, GBM, and CCRCC are the cancer types where PCIF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.918	.012	48	view →
GBM	OS	Quartile	All	0.686	0.267	.004	18	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	12	view →
PDAC	OS	Median	IV	0.973	0.482	.013	12	view →
LSCC	OS	Median	II,III,IV	0.911	0.752	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PCIF1–COAD (DFS)

Open the COAD breakdown →