PCGF7P

Across TCGA pan-cancer cohorts, PCGF7P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PCGF7P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PCGF7P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PCGF7P is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, HNSC, and LUSC are the cancer types where PCGF7P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PCGF7P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+0.306	<.001	11	view →
HNSC	All	All	+0.098	.005	7	view →
LUSC	All	All	+0.134	<.001	4	view →
LIHC	All	All	+0.074	.008	4	view →
KICH	Female	II,III,IV	−0.218	.001	3	view →
THCA	Male	II,III,IV	−0.133	.005	3	view →
STAD	Male	II,III,IV	+0.169	.008	2	view →
READ	Female	All	−0.182	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PCGF7P–COAD

Open the COAD breakdown →