PCGF6

Across TCGA pan-cancer cohorts, PCGF6 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PCGF6 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PCGF6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PCGF6 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, LUAD, and GBM are the cancer types where PCGF6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.962	0.810	.003	45	view →
LUAD	DFS	Tertile	III,IV	0.265	0.899	.038	6	view →
GBM	OS	Tertile	All	0.306	0.627	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PCGF6–LSCC (OS)

Open the LSCC breakdown →