PCGF6

Across TCGA cell cohorts, PCGF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,827 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCGF6-associated GO terms across cancer lineages are DNA replication initiation, Negative regulation of chromosome segregation, and DNA synthesis involved in DNA repair. Each is linked with PCGF6 in more than 17 cancer types. Because this analysis shows association rather than direction, both PCGF6-to-partner and partner-to-PCGF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by PCGF6-low versus PCGF6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF6→partner) and Y-score (partner→PCGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.215	+1.146	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome segregation →	+0.128	+0.867	.001	<.001	3	17
KIDNEY	DNA synthesis involved in DNA repair →	+0.081	+0.731	<.001	<.001	3	17
PANCREAS	Spindle elongation →	+0.341	+1.024	<.001	<.001	3	16
PANCREAS	Lagging strand elongation →	+0.374	+1.142	.006	<.001	3	16
PANCREAS	Spindle assembly →	+0.082	+0.781	<.001	.003	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,827 associations by consensus.

DNA replication initiation by PCGF6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →