Across TCGA patient cohorts, PCGF3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,160 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCGF3-associated genes across cancer lineages are CYTIP, PTPN7, and TIMD4. Each is linked with PCGF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCGF3-to-partner and partner-to-PCGF3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF3→partner) and Y-score (partner→PCGF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CYTIP →	-0.979	-0.686	<.001	<.001	3	2
LSCC	PTPN7 →	-0.782	-0.556	.002	.008	3	2
LSCC	TIMD4 →	-0.835	-0.623	.004	.003	3	2
BRCA	CTLA4 →	-0.989	-0.378	.002	.001	3	2
BRCA	CXXC4 →	+0.778	+0.332	.008	.006	3	2
LSCC	FUT7 →	-0.541	-0.506	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,160 associations by consensus.

Exploration

PCGF3 survival (RNA) · tumor vs normal (RNA) · all PCGF3 data types