Across TCGA cell cohorts, PCGF3 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCGF3-associated genes across cancer lineages are OR10R2, MRGPRG, and SLC32A1. Each is linked with PCGF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCGF3-to-partner and partner-to-PCGF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF3→partner) and Y-score (partner→PCGF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR10R2 →	+0.012	+3.772	<.001	.008	3	2
UPPER_AERODIGESTIVE_TRACT	MRGPRG →	+0.142	+4.736	<.001	.009	3	1
BLOOD_Leukemia	SLC32A1 →	+0.715	+4.223	<.001	.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.021	+4.365	<.001	.002	3	1
BLOOD_Leukemia	GSC →	+0.832	+3.948	.003	.003	3	1
BLOOD_Leukemia	TSHB →	+0.188	+3.691	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

PCGF3 survival (RNA) · tumor vs normal (RNA) · all PCGF3 data types