PCGF2

Across TCGA patient cohorts, PCGF2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCGF2-associated genes across cancer lineages are PIP4K2B, BTBD7, and MBTD1. Each is linked with PCGF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCGF2-to-partner and partner-to-PCGF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCGF2 versus PIP4K2B in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF2→partner) and Y-score (partner→PCGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIP4K2B →	+0.613	+0.424	<.001	<.001	3	6
HNSC	BTBD7 →	+0.513	+0.434	.001	.001	3	5
GBM	MBTD1 →	+0.453	+0.613	<.001	<.001	3	5
CCRCC	CLUHP3 →	+0.815	+0.369	.004	.001	3	5
BRCA	PGBD1 →	+0.683	+0.592	<.001	<.001	3	5
HNSC	NAA30 →	+0.619	+0.362	.006	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,848 associations by consensus.

PCGF2 vs PIP4K2B — UCEC

Explore this scatter interactively →