PCGF2

Across TCGA cell cohorts, PCGF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,088 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCGF2-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Locomotory exploration behavior, and Heterochromatin organization. Each is linked with PCGF2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PCGF2-to-partner and partner-to-PCGF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by PCGF2-low versus PCGF2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF2→partner) and Y-score (partner→PCGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.058	+0.795	<.001	<.001	3	9
STOMACH	Locomotory exploration behavior →	+0.209	+0.710	<.001	.009	3	9
STOMACH	Heterochromatin organization →	+0.056	+0.957	<.001	<.001	3	9
STOMACH	Epigenetic regulation of gene expression →	+0.054	+1.138	<.001	<.001	3	8
LARGE_INTESTINE	Lipoprotein transport →	+0.102	+0.641	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Lipoprotein localization →	+0.110	+0.838	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,088 associations by consensus.

Negative regulation of gene expression, epigenetic by PCGF2 expression — LUNG_SCLC

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