PCGF2

Across TCGA cell cohorts, PCGF2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PCGF2-associated genes across cancer lineages are CST8, H1-8, and OR8K3. Each is linked with PCGF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCGF2-to-partner and partner-to-PCGF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST8 grouped by PCGF2-low versus PCGF2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF2→partner) and Y-score (partner→PCGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CST8 →	+0.016	+5.807	<.001	.001	3	1
OVARY	H1-8 →	+0.059	+5.196	<.001	.005	3	1
OVARY	OR8K3 →	+0.035	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CST8 by PCGF2 expression — OVARY

Explore this box plot interactively →