PCGF1

Across TCGA pan-cancer cohorts, PCGF1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PCGF1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PCGF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PCGF1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, GBM, and HNSC are the cancer types where PCGF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.954	0.653	.003	32	view →
GBM	OS	Quartile	All	0.193	0.967	.014	9	view →
HNSC	DFS	Quartile	IV	0.538	0.812	.040	8	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PCGF1–LUAD (DFS)

Open the LUAD breakdown →