PCGF1

Across TCGA patient cohorts, PCGF1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,136 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCGF1-associated genes across cancer lineages are NUF2, CEP76, and CEP152. Each is linked with PCGF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCGF1-to-partner and partner-to-PCGF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCGF1 versus NUF2 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF1→partner) and Y-score (partner→PCGF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NUF2 →	+1.864	+0.661	.001	.002	3	4
LSCC	CEP76 →	+0.456	+0.212	.001	<.001	3	3
GBM	CEP152 →	+0.836	+0.648	<.001	<.001	3	3
UCEC	RBBP5 →	+0.425	+0.271	.005	.003	3	3
GBM	HELLS →	+1.465	+0.698	<.001	<.001	3	3
GBM	CENPL →	+0.751	+0.544	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,136 associations by consensus.

PCGF1 vs NUF2 — GBM

Explore this scatter interactively →