PCED1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCED1B protein abundance is significantly associated with the RNA expression of many other genes, with 7,449 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCED1B-associated genes across cancer lineages are GRAP2, DOCK8, and TESPA1. Each is linked with PCED1B in more than 2 cancer types. Because this analysis shows association rather than direction, both PCED1B-to-partner and partner-to-PCED1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCED1B versus GRAP2 in HNSC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCED1B→partner) and Y-score (partner→PCED1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGRAP2 →+1.197+1.082.001.00133
LSCCDOCK8 →+1.376+1.048<.001<.00133
LSCCTESPA1 →+1.058+0.846<.001.00133
HNSCC1orf162 →+1.381+1.005<.001.00233
LSCCPYHIN1 →+1.359+0.939<.001<.00133
HNSCPARP15 →+1.008+0.699.005.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,449 associations by consensus.

PCED1B vs GRAP2 — HNSC

Per-sample scatter of PCED1B vs GRAP2 in HNSC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration