PCED1B

Across TCGA cell cohorts, PCED1B mutation is significantly associated with the RNA expression of many other genes, with 424 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCED1B-associated genes across cancer lineages are STOX1, ALG6, and F11. Each is linked with PCED1B in more than 1 cancer types. Because this analysis shows association rather than direction, both PCED1B-to-partner and partner-to-PCED1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STOX1 grouped by PCED1B-low versus PCED1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCED1B→partner) and Y-score (partner→PCED1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	STOX1 →	+1.067	+3.212	.001	.006	3	2
LARGE_INTESTINE	ALG6 →	+0.551	+3.299	.002	.004	3	2
LARGE_INTESTINE	F11 →	+0.028	+2.882	.006	.001	3	2
LARGE_INTESTINE	SIRT1 →	+0.587	+3.212	.005	.006	3	2
LARGE_INTESTINE	MCAT →	+0.754	+3.212	<.001	.006	3	1
LARGE_INTESTINE	TNRC6B →	+0.766	+3.212	.001	.006	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 424 associations by consensus.

STOX1 by PCED1B expression — LARGE_INTESTINE

Explore this box plot interactively →