PCED1B

Across TCGA cell cohorts, PCED1B mutation is significantly associated with the mutation status of many other genes, with 5,771 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCED1B-associated genes across cancer lineages are SYNM, KIF1B, and PIK3R5. Each is linked with PCED1B in more than 3 cancer types. Because this analysis shows association rather than direction, both PCED1B-to-partner and partner-to-PCED1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYNM grouped by PCED1B-low versus PCED1B-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCED1B→partner) and Y-score (partner→PCED1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SYNM →	+4.415	+4.977	.007	.007	1	4
SOFT_TISSUE	KIF1B →	+5.502	+5.502	.003	.003	1	4
SKIN	PIK3R5 →	+3.117	+3.117	.009	.009	1	4
OVARY	SLC6A1 →	+5.415	+5.415	.004	.004	1	4
SOFT_TISSUE	BCOR →	+5.502	+5.502	.003	.003	1	4
BLOOD_Leukemia	SKIV2L →	+3.084	+3.084	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,771 associations by consensus.

SYNM by PCED1B expression — OVARY

Explore this box plot interactively →