PCDHGC5

Across TCGA patient cohorts, PCDHGC5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,268 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCDHGC5-associated genes across cancer lineages are APLNR, FOLR2, and RMI2. Each is linked with PCDHGC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHGC5-to-partner and partner-to-PCDHGC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGC5 versus APLNR in GBM, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC5→partner) and Y-score (partner→PCDHGC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APLNR →	+1.310	+0.313	.002	.006	3	3
BRCA	FOLR2 →	+1.447	+0.788	<.001	.002	3	3
BRCA	RMI2 →	-0.750	-0.661	.001	.004	3	3
BRCA	ADAMTSL1 →	+0.710	+0.853	<.001	.002	3	3
HNSC	STXBP5-AS1 →	+0.482	+0.660	.001	.005	3	3
BRCA	MAGI2-AS3 →	+0.767	+0.784	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,268 associations by consensus.

PCDHGC5 vs APLNR — GBM

Explore this scatter interactively →