PCDHGC4

Across TCGA patient cohorts, PCDHGC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGC4-associated proteins across cancer lineages are SSR3_S105, SEC11C, and SFRP2. Each is linked with PCDHGC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHGC4-to-partner and partner-to-PCDHGC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGC4 versus SSR3_S105 in OV, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC4→partner) and Y-score (partner→PCDHGC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SSR3_S105 →	-0.762	-0.241	.001	.001	3	3
HNSC	SEC11C →	-0.803	-0.443	.005	.005	3	3
BRCA	SFRP2 →	+0.786	+0.244	<.001	<.001	3	3
LSCC	HERPUD1 →	-0.505	-0.450	<.001	<.001	3	3
LSCC	LOXL2 →	+0.749	+0.463	<.001	<.001	3	3
LSCC	APC_S2830 →	+0.458	+0.524	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,500 associations by consensus.

PCDHGC4 vs SSR3_S105 — OV

Explore this scatter interactively →