PCDHGC4

Across TCGA patient cohorts, PCDHGC4 protein abundance is significantly associated with the protein abundance of many other proteins, with 742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGC4-associated proteins across cancer lineages are ATAD2B_S16, ATXN2L_S306, and BAHD1_S101. Each is linked with PCDHGC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGC4-to-partner and partner-to-PCDHGC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGC4 versus ATAD2B_S16 in GBM, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC4→partner) and Y-score (partner→PCDHGC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ATAD2B_S16 →	+1.024	+0.511	<.001	<.001	3	1
GBM	ATXN2L_S306 →	+0.938	+0.769	<.001	<.001	3	1
GBM	BAHD1_S101 →	-0.827	-0.370	.002	<.001	3	1
GBM	ADAM17 →	-0.382	-0.427	.003	<.001	3	1
GBM	BTN3A1 →	-0.471	-0.350	<.001	.001	3	1
GBM	BUD13_S240 →	+1.533	+0.668	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

PCDHGC4 vs ATAD2B_S16 — GBM

Explore this scatter interactively →